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Identification of Networks of Co-Occurring, Tumor-Related DNA Copy Number Changes Using a Genome-Wide Scoring Approach

Tumorigenesis is a multi-step process in which normal cells transform into malignant tumors following the accumulation of genetic mutations that enable them to evade the growth control checkpoints that would normally suppress their growth or result in apoptosis. It is therefore important to identify...

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Detalles Bibliográficos
Autores principales: Klijn, Christiaan, Bot, Jan, Adams, David J., Reinders, Marcel, Wessels, Lodewyk, Jonkers, Jos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791203/
https://www.ncbi.nlm.nih.gov/pubmed/20052266
http://dx.doi.org/10.1371/journal.pcbi.1000631