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Identification of Networks of Co-Occurring, Tumor-Related DNA Copy Number Changes Using a Genome-Wide Scoring Approach
Tumorigenesis is a multi-step process in which normal cells transform into malignant tumors following the accumulation of genetic mutations that enable them to evade the growth control checkpoints that would normally suppress their growth or result in apoptosis. It is therefore important to identify...
Autores principales: | Klijn, Christiaan, Bot, Jan, Adams, David J., Reinders, Marcel, Wessels, Lodewyk, Jonkers, Jos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791203/ https://www.ncbi.nlm.nih.gov/pubmed/20052266 http://dx.doi.org/10.1371/journal.pcbi.1000631 |
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