Dihydro-CDDO-Trifluoroethyl Amide (dh404), a Novel Nrf2 Activator, Suppresses Oxidative Stress in Cardiomyocytes

Targeting Nrf2 signaling appears to be an attractive approach for the treatment of maladaptive cardiac remodeling and dysfunction; however, pharmacological modulation of the Nrf2 pathway in the cardiovascular system remains to be established. Herein, we report that a novel synthetic triterpenoid der...

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Detalles Bibliográficos
Autores principales: Ichikawa, Tomonaga, Li, Jinqing, Meyer, Colin J., Janicki, Joseph S., Hannink, Mark, Cui, Taixing
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791441/
https://www.ncbi.nlm.nih.gov/pubmed/20027226
http://dx.doi.org/10.1371/journal.pone.0008391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791441/
https://www.ncbi.nlm.nih.gov/pubmed/20027226
http://dx.doi.org/10.1371/journal.pone.0008391

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