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Dihydro-CDDO-Trifluoroethyl Amide (dh404), a Novel Nrf2 Activator, Suppresses Oxidative Stress in Cardiomyocytes
Targeting Nrf2 signaling appears to be an attractive approach for the treatment of maladaptive cardiac remodeling and dysfunction; however, pharmacological modulation of the Nrf2 pathway in the cardiovascular system remains to be established. Herein, we report that a novel synthetic triterpenoid der...
Autores principales: | Ichikawa, Tomonaga, Li, Jinqing, Meyer, Colin J., Janicki, Joseph S., Hannink, Mark, Cui, Taixing |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791441/ https://www.ncbi.nlm.nih.gov/pubmed/20027226 http://dx.doi.org/10.1371/journal.pone.0008391 |
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