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Effect of the XRCC1 codon 399 polymorphism on the repair of vinyl chloride metabolite-induced DNA damage

BACKGROUND: Recent epidemiologic evidence suggests that the common polymorphism at amino acid residue 399 of the x-ray cross complementing-1 (XRCC1) protein, a key component of the base excision repair (BER) pathway for DNA damage, plays a significant role in the genetic variability of individuals i...

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Detalles Bibliográficos
Autores principales: Li, Yongliang, Long, Changmin, Lin, George, Marion, Marie-Jeanne, Freyer, Greg, Santella, Regina M., Brandt-Rauf, Paul W.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791826/
https://www.ncbi.nlm.nih.gov/pubmed/19822958
http://dx.doi.org/10.4103/1477-3163.56290