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Allergen Challenge Induces Ifng Dependent GTPases in the Lungs as Part of a Th1 Transcriptome Response in a Murine Model of Allergic Asthma

According to the current paradigm, allergic airway inflammation is mediated by Th2 cytokines and pro-inflammatory chemokines. Since allergic inflammation is self-limited, we hypothesized that allergen challenge simultaneously induces anti-inflammatory genes to counter-balance the effects of Th2 cyto...

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Detalles Bibliográficos
Autores principales: Dharajiya, Nilesh, Vaidya, Swapnil, Sinha, Mala, Luxon, Bruce, Boldogh, Istvan, Sur, Sanjiv
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791840/
https://www.ncbi.nlm.nih.gov/pubmed/20027288
http://dx.doi.org/10.1371/journal.pone.0008172