The Caenorhabditis elegans Werner Syndrome Protein Functions Upstream of ATR and ATM in Response to DNA Replication Inhibition and Double-Strand DNA Breaks

WRN-1 is the Caenorhabditis elegans homolog of the human Werner syndrome protein, a RecQ helicase, mutations of which are associated with premature aging and increased genome instability. Relatively little is known as to how WRN-1 functions in DNA repair and DNA damage signaling. Here, we take advan...

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Detalles Bibliográficos
Autores principales: Lee, Se-Jin, Gartner, Anton, Hyun, Moonjung, Ahn, Byungchan, Koo, Hyeon-Sook
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791846/
https://www.ncbi.nlm.nih.gov/pubmed/20062519
http://dx.doi.org/10.1371/journal.pgen.1000801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791846/
https://www.ncbi.nlm.nih.gov/pubmed/20062519
http://dx.doi.org/10.1371/journal.pgen.1000801

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