Role of the conserved glutamine 291 in the rat γ-aminobutyric acid transporter rGAT-1

We investigated the role of the Q291 glutamine residue in the functioning of the rat γ-aminobutyric acid (GABA) transporter GAT-1. Q291 mutants cannot transport GABA or give rise to transient, leak and transport-coupled currents even though they are targeted to the plasma membrane. Coexpression expe...

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Detalles Bibliográficos
Autores principales: Mari, S. A., Soragna, A., Castagna, M., Santacroce, M., Perego, C., Bossi, E., Peres, A., Sacchi, V. F.
Formato: Texto
Lenguaje:English
Publicado: Birkhäuser-Verlag 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792339/
https://www.ncbi.nlm.nih.gov/pubmed/16378241
http://dx.doi.org/10.1007/s00018-005-5512-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792339/
https://www.ncbi.nlm.nih.gov/pubmed/16378241
http://dx.doi.org/10.1007/s00018-005-5512-6

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