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Role of the conserved glutamine 291 in the rat γ-aminobutyric acid transporter rGAT-1

We investigated the role of the Q291 glutamine residue in the functioning of the rat γ-aminobutyric acid (GABA) transporter GAT-1. Q291 mutants cannot transport GABA or give rise to transient, leak and transport-coupled currents even though they are targeted to the plasma membrane. Coexpression expe...

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Detalles Bibliográficos
Autores principales:	Mari, S. A., Soragna, A., Castagna, M., Santacroce, M., Perego, C., Bossi, E., Peres, A., Sacchi, V. F.
Formato:	Texto
Lenguaje:	English
Publicado:	Birkhäuser-Verlag 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792339/ https://www.ncbi.nlm.nih.gov/pubmed/16378241 http://dx.doi.org/10.1007/s00018-005-5512-6

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