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Activation of the human FP prostanoid receptor disrupts mitosis progression and generates aneuploidy and polyploidy
Studies have shown prostaglandin F(2α) (PGF(2α) to be an endogenous tumor promoter in mouse models of skin carcinogenesis; however, the mechanisms by which PGF(2α) affects cell cycle events remain unknown. Here we performed cell cycle analyses on HEK cells stably expressing the human FP receptor and...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Birkhäuser-Verlag
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792351/ https://www.ncbi.nlm.nih.gov/pubmed/16378246 http://dx.doi.org/10.1007/s00018-005-5303-0 |