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Synthesis and Evaluation of L-Glutamic acid Analogs as Potential Anticancer Agents

Four N-(benzenesulfonyl)-L-glutamic acid bis(p-substituted phenylhydrazides) were synthesized and evaluated for anticancer activity in vitro in DU-145 and PC-3 prostate cancer and in COLO-205 colon cancer cell lines by MTT assay. The analog with the nitro group substitution exhibited potent activity...

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Detalles Bibliográficos
Autores principales: Vishwanathan, C. L., Deb, S., Jain, A., Lokhande, T., Juvekar, Aarti
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792474/
https://www.ncbi.nlm.nih.gov/pubmed/20046724
http://dx.doi.org/10.4103/0250-474X.41467