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Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials

AIMS: Use of inotropic agents in patients with heart failure (HF) has been limited by adverse effects on outcomes. However, administration of positive inotropes at lower doses and concomitant treatment with beta-blockers might increase benefit–risk ratio. We investigated the effects of low doses of...

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Detalles Bibliográficos
Autores principales: Metra, Marco, Eichhorn, Eric, Abraham, William T., Linseman, Jennifer, Böhm, Michael, Corbalan, Ramon, DeMets, David, De Marco, Teresa, Elkayam, Uri, Gerber, Michael, Komajda, Michel, Liu, Peter, Mareev, Vyacheslev, Perrone, Sergio V., Poole-Wilson, Philip, Roecker, Ellen, Stewart, Jennifer, Swedberg, Karl, Tendera, Michal, Wiens, Brian, Bristow, Michael R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792716/
https://www.ncbi.nlm.nih.gov/pubmed/19700774
http://dx.doi.org/10.1093/eurheartj/ehp338