Binding of NIR-conPK and NIR-6T to Astrocytomas and Microglial Cells: Evidence for a Protein Related to TSPO

PK 11195 and DAA1106 bind with high-affinity to the translocator protein (TSPO, formerly known as the peripheral benzodiazepine receptor). TSPO expression in glial cells increases in response to cytokines and pathological stimuli. Accordingly, [(11)C]-PK 11195 and [(11)C]-DAA1106 are recognized mole...

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Detalles Bibliográficos
Autores principales: Sexton, Michelle, Woodruff, Grace, Cudaback, Eiron, Kreitzer, Faith R., Xu, Cong, Lin, Yi Hsing, Möller, Thomas, Bai, Mingfeng, Manning, H. Charles, Bornhop, Darryl, Stella, Nephi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792720/
https://www.ncbi.nlm.nih.gov/pubmed/20020060
http://dx.doi.org/10.1371/journal.pone.0008271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792720/
https://www.ncbi.nlm.nih.gov/pubmed/20020060
http://dx.doi.org/10.1371/journal.pone.0008271

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