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rBPI(21) Promotes Lipopolysaccharide Aggregation and Exerts Its Antimicrobial Effects by (Hemi)fusion of PG-Containing Membranes

Antimicrobial peptides (AMPs) are important potential alternatives to conventional therapies against bacterial infections. rBPI(21) is a 21 kDa peptide based on the N-terminal region of the neutrophil bactericidal/permeability-increasing protein (BPI). This AMP possesses highly selective bactericida...

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Detalles Bibliográficos
Autores principales: Domingues, Marco M., Castanho, Miguel A. R. B., Santos, Nuno C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792722/
https://www.ncbi.nlm.nih.gov/pubmed/20027298
http://dx.doi.org/10.1371/journal.pone.0008385