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Regulation of Translational Efficiency by Disparate 5′ UTRs of PPARγ Splice Variants

The PPAR-γ gene encodes for at least 7 unique transcripts due to alternative splicing of five exons in the 5′-untranslated region (UTR). The translated region is encoded by exons 1–6, which are identical in all isoforms. This study investigated the role of the 5′-UTR in regulating the efficiency wit...

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Detalles Bibliográficos
Autores principales: McClelland, Shawn, Shrivastava, Roopali, Medh, Jheem D.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792960/
https://www.ncbi.nlm.nih.gov/pubmed/20016806
http://dx.doi.org/10.1155/2009/193413