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Use of Bacterially Expressed dsRNA to Downregulate Entamoeba histolytica Gene Expression

BACKGROUND: Modern RNA interference (RNAi) methodologies using small interfering RNA (siRNA) oligonucleotide duplexes or episomally synthesized hairpin RNA are valuable tools for the analysis of gene function in the protozoan parasite Entamoeba histolytica. However, these approaches still require ti...

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Detalles Bibliográficos
Autores principales: Solis, Carlos F., Santi-Rocca, Julien, Perdomo, Doranda, Weber, Christian, Guillén, Nancy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793006/
https://www.ncbi.nlm.nih.gov/pubmed/20037645
http://dx.doi.org/10.1371/journal.pone.0008424