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Bone Marrow Osteoblastic Niche: A New Model to Study Physiological Regulation of Megakaryopoiesis

BACKGROUND: The mechanism by which megakaryocytes (Mks) proliferate, differentiate, and release platelets into circulation are not well understood. Growing evidence indicates that a complex regulatory mechanism, involving cellular interactions, composition of the extracellular matrix and physical pa...

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Detalles Bibliográficos
Autores principales: Pallotta, Isabella, Lovett, Michael, Rice, William, Kaplan, David L., Balduini, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793008/
https://www.ncbi.nlm.nih.gov/pubmed/20027303
http://dx.doi.org/10.1371/journal.pone.0008359