Cargando…
Intraclonal Protein Expression Heterogeneity in Recombinant CHO Cells
Therapeutic glycoproteins have played a major role in the commercial success of biotechnology in the post-genomic era. But isolating recombinant mammalian cell lines for large-scale production remains costly and time-consuming, due to substantial variation and unpredictable stability of expression a...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793030/ https://www.ncbi.nlm.nih.gov/pubmed/20037651 http://dx.doi.org/10.1371/journal.pone.0008432 |