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Effect of PTTG on endogenous gene expression in HEK 293 cells

BACKGROUND: Pituitary tumor transforming gene (PTTG), also known as securin, is highly expressed in various tumors including pituitary, thyroid, colon, ovary, testis, lung, and breast. An overexpression of PTTG enhances cell proliferation, induces cellular transformation in vitro, and promotes tumor...

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Detalles Bibliográficos
Autores principales: Panguluri, Siva K, Kakar, Sham S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793268/
https://www.ncbi.nlm.nih.gov/pubmed/19958546
http://dx.doi.org/10.1186/1471-2164-10-577