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Systemic properties of metabolic networks lead to an epistasis-based model for heterosis

The genetic and molecular approaches to heterosis usually do not rely on any model of the genotype–phenotype relationship. From the generalization of Kacser and Burns’ biochemical model for dominance and epistasis to networks with several variable enzymes, we hypothesized that metabolic heterosis co...

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Detalles Bibliográficos
Autores principales: Fiévet, Julie B., Dillmann, Christine, de Vienne, Dominique
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793392/
https://www.ncbi.nlm.nih.gov/pubmed/19916003
http://dx.doi.org/10.1007/s00122-009-1203-2