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Pebble and Rock Band: Heuristic Resolution of Repeats and Scaffolding in the Velvet Short-Read de Novo Assembler

BACKGROUND: Despite the short length of their reads, micro-read sequencing technologies have shown their usefulness for de novo sequencing. However, especially in eukaryotic genomes, complex repeat patterns are an obstacle to large assemblies. PRINCIPAL FINDINGS: We present a novel heuristic algorit...

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Detalles Bibliográficos
Autores principales: Zerbino, Daniel R., McEwen, Gayle K., Margulies, Elliott H., Birney, Ewan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793427/
https://www.ncbi.nlm.nih.gov/pubmed/20027311
http://dx.doi.org/10.1371/journal.pone.0008407