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Hemozoin (Malarial Pigment) Directly Promotes Apoptosis of Erythroid Precursors

Severe malarial anemia is the most common syndrome of severe malaria in endemic areas. The pathophysiology of chronic malaria is characterised by a striking degree of abnormal development of erythroid precursors (dyserythropoiesis) and an inadequate erythropoietic response in spite of elevated level...

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Detalles Bibliográficos
Autores principales: Lamikanra, Abigail A., Theron, Michel, Kooij, Taco W. A., Roberts, David J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793514/
https://www.ncbi.nlm.nih.gov/pubmed/20041181
http://dx.doi.org/10.1371/journal.pone.0008446