Fiber Mediated Receptor Masking in Non-Infected Bystander Cells Restricts Adenovirus Cell Killing Effect but Promotes Adenovirus Host Co-Existence

The basic concept of conditionally replicating adenoviruses (CRAD) as oncolytic agents is that progenies generated from each round of infection will disperse, infect and kill new cancer cells. However, CRAD has only inhibited, but not eradicated tumor growth in xenograft tumor therapy, and CRAD ther...

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Detalles Bibliográficos
Autores principales: Rebetz, Johan, Na, Manli, Su, Changqing, Holmqvist, Bo, Edqvist, Anna, Nyberg, Cecilia, Widegren, Bengt, Salford, Leif G., Sjögren, Hans Olov, Arnberg, Niklas, Qian, Qijun, Fan, Xiaolong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793518/
https://www.ncbi.nlm.nih.gov/pubmed/20041185
http://dx.doi.org/10.1371/journal.pone.0008484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793518/
https://www.ncbi.nlm.nih.gov/pubmed/20041185
http://dx.doi.org/10.1371/journal.pone.0008484

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