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Fiber Mediated Receptor Masking in Non-Infected Bystander Cells Restricts Adenovirus Cell Killing Effect but Promotes Adenovirus Host Co-Existence
The basic concept of conditionally replicating adenoviruses (CRAD) as oncolytic agents is that progenies generated from each round of infection will disperse, infect and kill new cancer cells. However, CRAD has only inhibited, but not eradicated tumor growth in xenograft tumor therapy, and CRAD ther...
Autores principales: | Rebetz, Johan, Na, Manli, Su, Changqing, Holmqvist, Bo, Edqvist, Anna, Nyberg, Cecilia, Widegren, Bengt, Salford, Leif G., Sjögren, Hans Olov, Arnberg, Niklas, Qian, Qijun, Fan, Xiaolong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793518/ https://www.ncbi.nlm.nih.gov/pubmed/20041185 http://dx.doi.org/10.1371/journal.pone.0008484 |
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