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A Direct Phenotypic Comparison of siRNA Pools and Multiple Individual Duplexes in a Functional Assay

BACKGROUND: RNAi is a prominent tool for the identification of novel regulatory elements within complex cellular pathways. In invertebrates, RNAi is a relatively straightforward process, where large double-stranded RNA molecules initiate sequence-specific transcript destruction in target cells. In c...

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Detalles Bibliográficos
Autores principales: Parsons, Brendon D., Schindler, Anja, Evans, David H., Foley, Edan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793519/
https://www.ncbi.nlm.nih.gov/pubmed/20041186
http://dx.doi.org/10.1371/journal.pone.0008471