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A Direct Phenotypic Comparison of siRNA Pools and Multiple Individual Duplexes in a Functional Assay
BACKGROUND: RNAi is a prominent tool for the identification of novel regulatory elements within complex cellular pathways. In invertebrates, RNAi is a relatively straightforward process, where large double-stranded RNA molecules initiate sequence-specific transcript destruction in target cells. In c...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793519/ https://www.ncbi.nlm.nih.gov/pubmed/20041186 http://dx.doi.org/10.1371/journal.pone.0008471 |