Limited complementarity between U1 snRNA and a retroviral 5′ splice site permits its attenuation via RNA secondary structure

Multiple types of regulation are used by cells and viruses to control alternative splicing. In murine leukemia virus, accessibility of the 5′ splice site (ss) is regulated by an upstream region, which can fold into a complex RNA stem–loop structure. The underlying sequence of the structure itself is...

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Detalles Bibliográficos
Autores principales: Zychlinski, Daniela, Erkelenz, Steffen, Melhorn, Vanessa, Baum, Christopher, Schaal, Heiner, Bohne, Jens
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794156/
https://www.ncbi.nlm.nih.gov/pubmed/19854941
http://dx.doi.org/10.1093/nar/gkp694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794156/
https://www.ncbi.nlm.nih.gov/pubmed/19854941
http://dx.doi.org/10.1093/nar/gkp694

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