Cargando…

Limited complementarity between U1 snRNA and a retroviral 5′ splice site permits its attenuation via RNA secondary structure

Multiple types of regulation are used by cells and viruses to control alternative splicing. In murine leukemia virus, accessibility of the 5′ splice site (ss) is regulated by an upstream region, which can fold into a complex RNA stem–loop structure. The underlying sequence of the structure itself is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zychlinski, Daniela, Erkelenz, Steffen, Melhorn, Vanessa, Baum, Christopher, Schaal, Heiner, Bohne, Jens
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794156/ https://www.ncbi.nlm.nih.gov/pubmed/19854941 http://dx.doi.org/10.1093/nar/gkp694

Ejemplares similares

Human snRNA genes use polyadenylation factors to promote efficient transcription termination
por: O’Reilly, Dawn, et al.
Publicado: (2014)

A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP
por: Xue, Yuhua, et al.
Publicado: (2010)

The Myb domain of the largest subunit of SNAPc adopts different architectural configurations on U1 and U6 snRNA gene promoter sequences
por: Kang, Yoon Soon, et al.
Publicado: (2014)

Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin
por: Trejbalová, Kateřina, et al.
Publicado: (2011)

Human prefoldin modulates co-transcriptional pre-mRNA splicing
por: Payán-Bravo, Laura, et al.
Publicado: (2021)

Physiological state co-regulates thousands of mammalian mRNA splicing events at tandem splice sites and alternative exons
por: Szafranski, Karol, et al.
Publicado: (2014)

The pre-mRNA retention and splicing complex controls tRNA maturation by promoting TAN1 expression
por: Zhou, Yang, et al.
Publicado: (2013)

Alternative linker histone permits fast paced nuclear divisions in early Drosophila embryo
por: Henn, László, et al.
Publicado: (2020)

The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II
por: Carnesecchi, Julie, et al.
Publicado: (2021)

RNA-dependent dynamic histone acetylation regulates MCL1 alternative splicing
por: Khan, Dilshad H., et al.
Publicado: (2014)

TIP60 represses activation of endogenous retroviral elements
por: Rajagopalan, Deepa, et al.
Publicado: (2018)

Silenced yeast chromatin is maintained by Sir2 in preference to permitting histone acetylations for efficient NER
por: Irizar, Agurtzane, et al.
Publicado: (2010)

Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource
por: Nanan, Kyster K., et al.
Publicado: (2017)

Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors
por: Shi, Yao, et al.
Publicado: (2021)

CDK12/13 promote splicing of proximal introns by enhancing the interaction between RNA polymerase II and the splicing factor SF3B1
por: Panzeri, Valentina, et al.
Publicado: (2023)

hnRNP G/RBMX enhances HPV16 E2 mRNA splicing through a novel splicing enhancer and inhibits production of spliced E7 oncogene mRNAs
por: Hao, Chengyu, et al.
Publicado: (2022)

The adenovirus L4-22K protein regulates transcription and RNA splicing via a sequence-specific single-stranded RNA binding
por: Lan, Susan, et al.
Publicado: (2017)

The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator
por: Pedrotti, Simona, et al.
Publicado: (2012)

The splice variants of UBF differentially regulate RNA polymerase I transcription elongation in response to ERK phosphorylation
por: Stefanovsky, Victor Y., et al.
Publicado: (2008)

Evolutionarily conserved autoregulation of alternative pre-mRNA splicing by ribosomal protein L10a
por: Takei, Satomi, et al.
Publicado: (2016)

An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana
por: Streitner, Corinna, et al.
Publicado: (2012)

ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing
por: Gatto, Sole, et al.
Publicado: (2017)

CHD8 suppression impacts on histone H3 lysine 36 trimethylation and alters RNA alternative splicing
por: Kerschbamer, Emanuela, et al.
Publicado: (2022)

Position-dependent and neuron-specific splicing regulation by the CELF family RNA-binding protein UNC-75 in Caenorhabditis elegans
por: Kuroyanagi, Hidehito, et al.
Publicado: (2013)

CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo
por: Gu, Bo, et al.
Publicado: (2013)

The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress
por: Lemaitre, Florence, et al.
Publicado: (2022)

Accumulation of long-term transcriptionally active integrated retroviral vectors in active promoters and enhancers
por: Šenigl, Filip, et al.
Publicado: (2017)

HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression
por: Srinivasachar Badarinarayan, Smitha, et al.
Publicado: (2020)

Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites
por: Siegel, Tim Nicolai, et al.
Publicado: (2010)

The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit
por: Zraly, Claudia B., et al.
Publicado: (2012)

Activation of alternative Jdp2 promoters and functional protein isoforms in T-cell lymphomas by retroviral insertion mutagenesis
por: Rasmussen, Mads Heilskov, et al.
Publicado: (2009)

Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation
por: Song, Yanhua, et al.
Publicado: (2021)

SRRM2 organizes splicing condensates to regulate alternative splicing
por: Xu, Shaohai, et al.
Publicado: (2022)

The PRP6-like splicing factor STA1 is involved in RNA-directed DNA methylation by facilitating the production of Pol V-dependent scaffold RNAs
por: Dou, Kun, et al.
Publicado: (2013)

Active endogenous retroviral elements in human pluripotent stem cells play a role in regulating host gene expression
por: Zhang, Tianzhe, et al.
Publicado: (2022)

Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells
por: Zhou, Rui, et al.
Publicado: (2017)

c-MYC empowers transcription and productive splicing of the oncogenic splicing factor Sam68 in cancer
por: Caggiano, Cinzia, et al.
Publicado: (2019)

Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing
por: Glaich, Ohad, et al.
Publicado: (2019)

The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3′-UTR truncation in round spermatids
por: Berkovits, Binyamin D., et al.
Publicado: (2012)

Extended base pair complementarity between U1 snRNA and the 5′ splice site does not inhibit splicing in higher eukaryotes, but rather increases 5′ splice site recognition
por: Freund, Marcel, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_pdgbsh3tmhqq3pmiplihosfoh2