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Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines

The X chromosome-linked inhibitor of apoptosis protein (XIAP) is the most potent intrinsic caspase inhibitor and plays an important role in the maintenance of intestinal epithelial integrity. The RNA binding protein, HuR, regulates the stability and translation of many target transcripts. Here, we r...

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Detalles Bibliográficos
Autores principales: Zhang, Xian, Zou, Tongtong, Rao, Jaladanki N., Liu, Lan, Xiao, Lan, Wang, Peng-Yuan, Cui, Yu-Hong, Gorospe, Myriam, Wang, Jian-Ying
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794158/
https://www.ncbi.nlm.nih.gov/pubmed/19825980
http://dx.doi.org/10.1093/nar/gkp755