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Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotides
Gene editing mediated by oligonucleotides has been shown to induce stable single base alterations in genomic DNA in both prokaryotic and eukaryotic organisms. However, the low frequencies of gene repair have limited its applicability for both basic manipulation of genomic sequences and for the devel...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794159/ https://www.ncbi.nlm.nih.gov/pubmed/19854937 http://dx.doi.org/10.1093/nar/gkp757 |