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Sub-cellular trafficking and functionality of 2′-O-methyl and 2′-O-methyl-phosphorothioate molecular beacons

Molecular beacons (MBs) have shown great potential for the imaging of RNAs within single living cells; however, the ability to perform accurate measurements of RNA expression can be hampered by false-positives resulting from nonspecific interactions and/or nuclease degradation. These false-positives...

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Detalles Bibliográficos
Autores principales: Chen, Antony K., Behlke, Mark A., Tsourkas, Andrew
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794186/
https://www.ncbi.nlm.nih.gov/pubmed/19820111
http://dx.doi.org/10.1093/nar/gkp837