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Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs
Numerous regulatory genes have G-rich regions that can potentially form quadruplex structures, possibly playing a role in transcription regulation. We studied a G-rich sequence in the BCL2 gene 176-bp upstream of the P1 promoter for G-quadruplex formation. Using circular dichroism (CD), thermal dena...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794188/ https://www.ncbi.nlm.nih.gov/pubmed/19820116 http://dx.doi.org/10.1093/nar/gkp840 |