Selection of hyperfunctional siRNAs with improved potency and specificity

One critical step in RNA interference (RNAi) experiments is to design small interfering RNAs (siRNAs) that can greatly reduce the expression of the target transcripts, but not of other unintended targets. Although various statistical and computational approaches have been attempted, this remains a c...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowei, Wang, Xiaohui, Varma, Rajeev K., Beauchamp, Lesslie, Magdaleno, Susan, Sendera, Timothy J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794195/
https://www.ncbi.nlm.nih.gov/pubmed/19846596
http://dx.doi.org/10.1093/nar/gkp864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794195/
https://www.ncbi.nlm.nih.gov/pubmed/19846596
http://dx.doi.org/10.1093/nar/gkp864

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