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Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi

BACKGROUND: Wolbachia (wBm) is an obligate endosymbiotic bacterium of Brugia malayi, a parasitic filarial nematode of humans and one of the causative agents of lymphatic filariasis. There is a pressing need for new drugs against filarial parasites, such as B. malayi. As wBm is required for B. malayi...

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Detalles Bibliográficos
Autores principales: Holman, Alexander G, Davis, Paul J, Foster, Jeremy M, Carlow, Clotilde KS, Kumar, Sanjay
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794283/
https://www.ncbi.nlm.nih.gov/pubmed/19943957
http://dx.doi.org/10.1186/1471-2180-9-243