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Functional features of gene expression profiles differentiating gastrointestinal stromal tumours according to KIT mutations and expression
BACKGROUND: Gastrointestinal stromal tumours (GISTs) represent a heterogeneous group of tumours of mesenchymal origin characterized by gain-of-function mutations in KIT or PDGFRA of the type III receptor tyrosine kinase family. Although mutations in either receptor are thought to drive an early onco...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794290/ https://www.ncbi.nlm.nih.gov/pubmed/19943934 http://dx.doi.org/10.1186/1471-2407-9-413 |