Cargando…

Functional features of gene expression profiles differentiating gastrointestinal stromal tumours according to KIT mutations and expression

BACKGROUND: Gastrointestinal stromal tumours (GISTs) represent a heterogeneous group of tumours of mesenchymal origin characterized by gain-of-function mutations in KIT or PDGFRA of the type III receptor tyrosine kinase family. Although mutations in either receptor are thought to drive an early onco...

Descripción completa

Detalles Bibliográficos
Autores principales: Ostrowski, Jerzy, Polkowski, Marcin, Paziewska, Agnieszka, Skrzypczak, Magdalena, Goryca, Krzysztof, Rubel, Tymon, Kokoszyñska, Katarzyna, Rutkowski, Piotr, Nowecki, Zbigniew I, Dobosz, Anna Jerzak Vel, Jarosz, Dorota, Ruka, Wlodzimierz, Wyrwicz, Lucjan S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794290/
https://www.ncbi.nlm.nih.gov/pubmed/19943934
http://dx.doi.org/10.1186/1471-2407-9-413