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An Adequately Robust Early TNF-α Response Is a Hallmark of Survival Following Trauma/Hemorrhage

BACKGROUND: Trauma/hemorrhagic shock (T/HS) results in cytokine-mediated acute inflammation that is generally considered detrimental. METHODOLOGY/PRINCIPAL FINDINGS: Paradoxically, plasma levels of the early inflammatory cytokine TNF-α (but not IL-6, IL-10, or NO(2) (-)/NO(3) (-)) were significantly...

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Detalles Bibliográficos
Autores principales: Namas, Rajaie, Ghuma, Ali, Torres, Andres, Polanco, Patricio, Gomez, Hernando, Barclay, Derek, Gordon, Lisa, Zenker, Sven, Kim, Hyung Kook, Hermus, Linda, Zamora, Ruben, Rosengart, Matthew R., Clermont, Gilles, Peitzman, Andrew, Billiar, Timothy R., Ochoa, Juan, Pinsky, Michael R., Puyana, Juan Carlos, Vodovotz, Yoram
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794373/
https://www.ncbi.nlm.nih.gov/pubmed/20027315
http://dx.doi.org/10.1371/journal.pone.0008406