MEF2C Silencing Attenuates Load-Induced Left Ventricular Hypertrophy by Modulating mTOR/S6K Pathway in Mice

BACKGROUND: The activation of the members of the myocyte enhancer factor-2 family (MEF2A, B, C and D) of transcription factors promotes cardiac hypertrophy and failure. However, the role of its individual components in the pathogenesis of cardiac hypertrophy remains unclear. METHODOLOGY/PRINCIPAL FI...

Descripción completa

Detalles Bibliográficos
Autores principales: Pereira, Ana Helena M., Clemente, Carolina F. M. Z., Cardoso, Alisson C., Theizen, Thais H., Rocco, Silvana A., Judice, Carla C., Guido, Maria Carolina, Pascoal, Vinícius D. B., Lopes-Cendes, Iscia, Souza, José Roberto M., Franchini, Kleber G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794538/
https://www.ncbi.nlm.nih.gov/pubmed/20041152
http://dx.doi.org/10.1371/journal.pone.0008472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794538/
https://www.ncbi.nlm.nih.gov/pubmed/20041152
http://dx.doi.org/10.1371/journal.pone.0008472

Ejemplares similares