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Extraordinary Molecular Evolution in the PRDM9 Fertility Gene

Recent work indicates that allelic incompatibility in the mouse PRDM9 (Meisetz) gene can cause hybrid male sterility, contributing to genetic isolation and potentially speciation. The only phenotype of mouse PRDM9 knockouts is a meiosis I block that causes sterility in both sexes. The PRDM9 gene enc...

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Detalles Bibliográficos
Autores principales: Thomas, James H., Emerson, Ryan O., Shendure, Jay
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794550/
https://www.ncbi.nlm.nih.gov/pubmed/20041164
http://dx.doi.org/10.1371/journal.pone.0008505