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Extraordinary Molecular Evolution in the PRDM9 Fertility Gene
Recent work indicates that allelic incompatibility in the mouse PRDM9 (Meisetz) gene can cause hybrid male sterility, contributing to genetic isolation and potentially speciation. The only phenotype of mouse PRDM9 knockouts is a meiosis I block that causes sterility in both sexes. The PRDM9 gene enc...
Autores principales: | Thomas, James H., Emerson, Ryan O., Shendure, Jay |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794550/ https://www.ncbi.nlm.nih.gov/pubmed/20041164 http://dx.doi.org/10.1371/journal.pone.0008505 |
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