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F11-Mediated Inhibition of RhoA Signalling Enhances the Spread of Vaccinia Virus In Vitro and In Vivo in an Intranasal Mouse Model of Infection

The cortical actin cytoskeleton beneath the plasma membrane represents a physical barrier that vaccinia virus has to overcome during its exit from an infected cell. Previous observations using overexpression and pharmacological approaches suggest that vaccinia enhances its release by modulating the...

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Detalles Bibliográficos
Autores principales: Cordeiro, João V., Guerra, Susana, Arakawa, Yoshiki, Dodding, Mark P., Esteban, Mariano, Way, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794559/
https://www.ncbi.nlm.nih.gov/pubmed/20041165
http://dx.doi.org/10.1371/journal.pone.0008506