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TLR4 signaling induced by lipopolysacharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer

Toll-like receptors (TLRs) expressed on immune cells trigger inflammatory responses. TLRs are also expressed on ovarian cancer (OvCa) cells, but the consequences of signaling via the TLR4/MyD88 pathway in these cells are unclear. Here, TLR4 and MyD88 expression in OvCa tissues (n=20) and cell lines...

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Detalles Bibliográficos
Autores principales: Szajnik, Marta, Szczepanski, Miroslaw J., Czystowska, Malgorzata, Elishaev, Esther, Mandapathil, Magis, Nowak-Markwitz, Ewa, Spaczynski, Marek, Whiteside, Theresa L.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794996/
https://www.ncbi.nlm.nih.gov/pubmed/19826413
http://dx.doi.org/10.1038/onc.2009.289