Matrix density-induced mechanoregulation of breast cell phenotype, signaling, and gene expression through a FAK-ERK linkage

Mammographically dense breast tissue is one of the greatest risk factors for developing breast carcinoma, yet the associated molecular mechanisms remain largely unknown. Importantly, regions of high breast density are associated with increased stromal collagen and epithelial cell content. We set out...

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Detalles Bibliográficos
Autores principales: Provenzano, Paolo P., Inman, David R., Eliceiri, Kevin W., Keely, Patricia J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795025/
https://www.ncbi.nlm.nih.gov/pubmed/19826415
http://dx.doi.org/10.1038/onc.2009.299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795025/
https://www.ncbi.nlm.nih.gov/pubmed/19826415
http://dx.doi.org/10.1038/onc.2009.299

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