Quantitative high-throughput screening identifies inhibitors of anthrax-induced cell death

Here, we report the results of a quantitative high-throughput screen (qHTS) measuring the endocytosis and translocation of a β-lactamase-fused-lethal factor and the identification of small molecules capable of obstructing the process of anthrax toxin internalization. Several small molecules protect...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Ping Jun, Hobson, John P., Southall, Noel, Qiu, Cunping, Thomas, Craig J., Lu, Jiamo, Inglese, James, Zheng, Wei, Leppla, Stephen H., Bugge, Thomas H., Austin, Christopher P., Liu, Shihui
Formato: Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795356/
https://www.ncbi.nlm.nih.gov/pubmed/19540764
http://dx.doi.org/10.1016/j.bmc.2009.05.054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795356/
https://www.ncbi.nlm.nih.gov/pubmed/19540764
http://dx.doi.org/10.1016/j.bmc.2009.05.054

Ejemplares similares