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Glycogen synthase kinase-3: a new therapeutic target in renal cell carcinoma

BACKGROUND: Renal cell carcinoma (RCC) is highly resistant to chemotherapy because of a high apoptotic threshold. Recent evidences suggest that GSK-3β positively regulates human pancreatic cancer and leukaemia cell survival in part through regulation of nuclear factor (NF-κB)-mediated expression of...

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Detalles Bibliográficos
Autores principales: Bilim, V, Ougolkov, A, Yuuki, K, Naito, S, Kawazoe, H, Muto, A, Oya, M, Billadeau, D, Motoyama, T, Tomita, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795437/
https://www.ncbi.nlm.nih.gov/pubmed/19920820
http://dx.doi.org/10.1038/sj.bjc.6605437