Cargando…

Analysis of the mitotic exit control system using locked levels of stable mitotic cyclin

Cyclin-dependent kinase (Cdk) both promotes mitotic entry (spindle assembly and anaphase) and inhibits mitotic exit (spindle disassembly and cytokinesis), leading to an elegant quantitative hypothesis that a single cyclin oscillation can function as a ratchet to order these events. This ratchet is a...

Descripción completa

Detalles Bibliográficos
Autores principales: Drapkin, Benjamin J, Lu, Ying, Procko, Andrea L, Timney, Benjamin L, Cross, Frederick R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795472/
https://www.ncbi.nlm.nih.gov/pubmed/19920813
http://dx.doi.org/10.1038/msb.2009.78