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Dissection of a complex transcriptional response using genome-wide transcriptional modelling

Modern genomics technologies generate huge data sets creating a demand for systems level, experimentally verified, analysis techniques. We examined the transcriptional response to DNA damage in a human T cell line (MOLT4) using microarrays. By measuring both mRNA accumulation and degradation over a...

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Detalles Bibliográficos
Autores principales: Barenco, Martino, Brewer, Daniel, Papouli, Efterpi, Tomescu, Daniela, Callard, Robin, Stark, Jaroslav, Hubank, Michael
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795478/
https://www.ncbi.nlm.nih.gov/pubmed/19920812
http://dx.doi.org/10.1038/msb.2009.84