LD-Spline: Mapping SNPs on genotyping platforms to genomic regions using patterns of linkage disequilibrium

BACKGROUND: Gene-centric analysis tools for genome-wide association study data are being developed both to annotate single locus statistics and to prioritize or group single nucleotide polymorphisms (SNPs) prior to analysis. These approaches require knowledge about the relationships between SNPs on...

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Detalles Bibliográficos
Autores principales: Bush, William S, Chen, Guanhua, Torstenson, Eric S, Ritchie, Marylyn D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795743/
https://www.ncbi.nlm.nih.gov/pubmed/19954552
http://dx.doi.org/10.1186/1756-0381-2-7