Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report

BACKGROUND: MLH1 is one of six known genes responsible for DNA mismatch repair (MMR), whose inactivation leads to HNPCC. It is important to develop genotype-phenotype correlations for HNPCC, as is being done for other hereditary cancer syndromes, in order to guide surveillance and treatment strategi...

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Detalles Bibliográficos
Autores principales: Valenzuela, Cristian D, Moore, Harvey G, Huang, William C, Reich, Elsa W, Yee, Herman, Ostrer, Harry, Pachter, H Leon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795749/
https://www.ncbi.nlm.nih.gov/pubmed/19995443
http://dx.doi.org/10.1186/1477-7819-7-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795749/
https://www.ncbi.nlm.nih.gov/pubmed/19995443
http://dx.doi.org/10.1186/1477-7819-7-94

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