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Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in MLH1: Case report
BACKGROUND: MLH1 is one of six known genes responsible for DNA mismatch repair (MMR), whose inactivation leads to HNPCC. It is important to develop genotype-phenotype correlations for HNPCC, as is being done for other hereditary cancer syndromes, in order to guide surveillance and treatment strategi...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795749/ https://www.ncbi.nlm.nih.gov/pubmed/19995443 http://dx.doi.org/10.1186/1477-7819-7-94 |