In vivo selection of tumor-targeting RNA motifs

In an effort to target the in vivo context of tumor-specific moieties, a large library of nuclease-resistant RNA oligonucleotides was screened in tumor-bearing mice to identify candidate molecules with the ability to localize to hepatic colon cancer metastases. One of the selected molecules is an RN...

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Detalles Bibliográficos
Autores principales: Mi, Jing, Liu, Yingmiao, Rabbani, Zahid N., Yang, Zhongguang, Urban, Johannes H, Sullenger, Bruce A., Clary, Bryan M.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795795/
https://www.ncbi.nlm.nih.gov/pubmed/19946274
http://dx.doi.org/10.1038/nchembio.277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795795/
https://www.ncbi.nlm.nih.gov/pubmed/19946274
http://dx.doi.org/10.1038/nchembio.277

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