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Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

Previously, mapping of the 9p23-24 amplicon in esophageal cancer cell lines led us to the positional cloning of GASC1 (gene amplified in squamous cell carcinoma 1), which encodes a nuclear protein with a Jumonji C (JmjC) domain that catalyzes lysine (K) demethylation of histones. However, the transf...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Bollig-Fischer, Aliccia, Kreike, Bas, van de Vijver, Marc J., Abrams, Judith, Ethier, Stephen P., Yang, Zeng-Quan
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795798/
https://www.ncbi.nlm.nih.gov/pubmed/19784073
http://dx.doi.org/10.1038/onc.2009.297